EU Openscreen

Automated Sample Storage in Europe’s Largest Screening Network for Chemical Biology

EU-OPENSCREEN operates a publicly accessible database containing a unique collection of chemical substances. With more than 20 connected high-throughput screening and chemistry facilities at partner sites across ten European countries, EU-OPENSCREEN provides researchers with access to leading technologies to explore and develop their own bioactive compounds.

Process of Automated Sample Storage

For the highly complex process of automated storage of substances in dimethyl sulfoxide (DMSO) at –20 °C, LVL SAFE® 2D Tubes and Racks from LVL technologies are used—together with the LVL SAFE® 8-channel and 96-channel Capper/Decapper.

Thanks to the high quality and tight sealing of the tubes, the reliable readability of the codes, and excellent compatibility with automated systems, a smooth workflow is ensured. More than 100,000 samples have already been stored in LVL SAFE® 2D Tubes.

Synergy of Chemical Expertise and Biomedicine

Biologically active compounds are used in numerous fields, including pharmaceuticals, crop protection, cosmetics, the food industry, and environmental protection. A key technology for discovering new bioactive substances is high-throughput screening of large compound libraries.

EU-OPENSCREEN is a European Research Infrastructure Consortium (ERIC) focused on chemical biology and the early identification of bioactive compounds. Its goal is to provide scientists in Europe with access to individually selected compounds for scientific studies and experiments.

The scope ranges from transferring thousands of substances at fixed concentrations to the detailed provision of individual compounds at variable dosages for subsequent development steps. Bioassays to assess biological activity are also conducted.

Samples and Processes

  1. Lieferung neuer Substanzen in LVL SAFE® 2D Tubes
  2. Probenprozessierung im Pipettierroboter
  3. Automatisiertes Capping/Decapping mit dem LVL SAFE® 96-Kanal Capper/Decapper
  4. Kontrolliertes Einfrieren und Einlagerung im vollautomatisierten Lagersystem bei –20 °C
  5. Anfragen europäischer Partner zur Verwendung zu Forschungszwecken
  6. Automatisierte Probenselektion und Überführung in MTPs für den Versand
  7. Nutzung in wissenschaftlichen Studien und Experimenten

Detailed Process Steps

  • Delivery of new substances in LVL SAFE® 2D Tubes
  • Sample processing with pipetting robots
  • Automated capping/decapping using the LVL SAFE® 96-channel Capper/Decapper
  • Controlled freezing and storage in the fully automated –20 °C storage system
  • Requests from European partners for research purposes
  • Automated sample selection and transfer to MTPs for shipment
  • Use in scientific studies and experiments

LVL Technologies Products Used

Tubes

  • LVL SAFE® 2D Tubes LX1000 (External thread)

Devices

  • LVL SAFE® 96-Channel Capper/Decapper
  • LVL SAFE® 8-Channel Capper/Decapper (Handheld device)

Customer Feedback: User Experience & Benefits

Compatibility with Equipment and Workflow

  • 2D codes readable both by machine and manually, on the bottom and side
  • System-compatible with pipetting robots, freezing robotics, and nitrogen storage systems
  • Excellent handling for manual processes
  • Suitable for all temperature ranges (room temperature to –196 °C)

Product Portfolio & Advantages

  • Tubes with external threads to reduce contamination
  • Suitable for DMSO and other organic solvents
  • IATA-certified TPE seal – safe and chemical-resistant
  • High transparency, even with colored solutions

Product and Delivery Quality

  • Very low failure rate with the highest product quality
  • Flexible purchase and delivery options
  • Fast, reliable delivery

Capper/Decapper: Efficient & Reliable

  • No adapter plates required
  • Optimal coordination between rack, capper, and tube
  • Stable, robust systems—even under high process loads

“We have valued the excellent collaboration with LVL technologies for many years. The company stands out for its outstanding expertise, particularly in the optimal configuration of the product portfolio. The technical service is extremely pleasant and easy to use. We experience very fast response times and greatly appreciate the partnership.”

Reference

David Garcia Lopez
Lab Automation Manager
EU-OPENSCREEN ERIC
Robert-Rössle-Str. 10, 13125 Berlin

www.eu-openscreen.eu
Video auf YouTube

Contact

Tobias Haessner
LVL technologies GmbH & Co. KG
Theodor-Storm-Str. 17, 74564 Crailsheim
T +49 7951 95613-45
M +49 175 7283454

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