{"id":62184,"date":"2023-08-15T19:59:45","date_gmt":"2023-08-15T17:59:45","guid":{"rendered":"https:\/\/lvl-technologies.com\/?page_id=62184"},"modified":"2026-05-11T12:49:46","modified_gmt":"2026-05-11T10:49:46","slug":"safe-2d-tubes-faq","status":"publish","type":"page","link":"https:\/\/lvl-technologies.com\/en\/safe-2d-tubes-faq\/","title":{"rendered":"SAFE\u00ae 2D Tubes FAQ"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_empty_space][vc_custom_heading text=&#8221;SAFE\u00ae 2D Tubes FAQ \u2013<br \/>\nFormats, Applications &#038; Benefits&#8221; font_container=&#8221;tag:h1|text_align:left|color:%23009fe3&#8243; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_empty_space][vc_column_text css=&#8221;&#8221;]SAFE\u00ae 2D tubes from LVL technologies are specialized sample containers designed for secure, automatable, and traceable storage of biological and chemical samples. In this <strong>FAQ section<\/strong>, we answer key questions regarding formats, material properties, traceability, and areas of application.<\/p>\n<p>The <a href=\"https:\/\/lvl-technologies.com\/en\/safe-tubes\/\" target=\"_blank\" rel=\"noopener\">SAFE\u00ae 2D tubes<\/a> meet the requirements of modern laboratory environments, particularly in biobanking, pharmaceutical research, and diagnostics. Thanks to ANSI\/SBS compatibility, they integrate seamlessly into automated storage systems, liquid-handling platforms, and rack readers. The 2D DataMatrix code embedded in the tube bottom enables unambiguous machine-readable identification of each sample and supports digital traceability from sample receipt to long-term archiving.<\/p>\n<p>The tubes are made of SAFE\u00ae L3 Medical Polypropylene and, in combination with a validated closure system, ensure reliable sealing even during cryogenic storage down to \u2212196 \u00b0C. This FAQ demonstrates how SAFE\u00ae 2D tubes reduce errors, meet regulatory requirements, and streamline daily laboratory workflows.[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=&#8221;Formats &#038; Technical Basics&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23363636&#8243; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_empty_space][vc_tta_accordion section_title_tag=&#8221;h3&#8243; style=&#8221;flat&#8221; color=&#8221;blue&#8221; spacing=&#8221;5&#8243; c_position=&#8221;left&#8221; active_section=&#8221;&#8221; no_fill=&#8221;true&#8221; collapsible_all=&#8221;true&#8221; faq_schema=&#8221;yes&#8221; el_class=&#8221;gf-faq-schema&#8221;][vc_tta_section title=&#8221;What formats are available for SAFE\u00ae 2D tubes?&#8221; tab_id=&#8221;1777974625852-7f8cecdb-7109&#8243;][vc_column_text css=&#8221;&#8221;]SAFE\u00ae 2D tubes are available in 24-, 48-, and 96-position formats. The arrangement complies with ANSI\/SBS geometric requirements, ensuring compatibility with automated storage systems, rack readers, and liquid-handling platforms.<\/p>\n<p>Depending on the application, variants with internal or external threads are available. For cryogenic applications, external threads are preferred as they reduce the risk of sample liquid entering the thread area.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;What does &#8216;2D&#8217; mean in 2D tubes?&#8221; tab_id=&#8221;1777974625866-a316867e-ab1c&#8221;][vc_column_text css=&#8221;&#8221;]\u201c2D\u201d refers to the 2D DataMatrix code embedded in the tube bottom.<\/p>\n<p>The code is engraved directly into the material using a fiber laser. Engraving depth is approximately 50 \u00b5m, creating a three-dimensional, abrasion-resistant structure.<\/p>\n<p>The codes achieve ISO 15415 quality grades A or B and remain reliably readable even after mechanical stress and cryogenic storage.<\/p>\n<p>Each tube ID is individually generated, checked against the complete historical production database, and verified by rack. Duplicate codes are therefore excluded.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;How do SAFE\u00ae 2D tubes differ from conventional sample tubes?&#8221; tab_id=&#8221;1777974723708-c9d46b6d-d2b7&#8243;][vc_column_text css=&#8221;&#8221;]Compared to manually labeled standard tubes, SAFE\u00ae 2D tubes provide machine-readable, unique identification.<\/p>\n<p>They are additionally designed for:<\/p>\n<ul>\n<li>Automated pick-and-place processes<\/li>\n<li>Simultaneous rack scanning<\/li>\n<li>Validated cryostability<\/li>\n<li>Documented material purity<\/li>\n<li>Reproducible capping \u2013 suitable for high-throughput and long-term archival workflows<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Are SAFE\u00ae 2D tubes SBS-compliant?&#8221; tab_id=&#8221;1777974773943-0810a22a-b5bd&#8221;][vc_column_text css=&#8221;&#8221;]Yes. The tubes and racks meet the geometric requirements of the ANSI\/SBS standard, allowing use in common automated storage and robotic systems.[\/vc_column_text][\/vc_tta_section][\/vc_tta_accordion][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=&#8221;Cryogenic Storage &amp; Material Properties&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23363636&#8243; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_empty_space][vc_tta_accordion section_title_tag=&#8221;h3&#8243; style=&#8221;flat&#8221; color=&#8221;blue&#8221; spacing=&#8221;5&#8243; c_position=&#8221;left&#8221; active_section=&#8221;&#8221; no_fill=&#8221;true&#8221; collapsible_all=&#8221;true&#8221; faq_schema=&#8221;yes&#8221; el_class=&#8221;gf-faq-schema&#8221;][vc_tta_section title=&#8221;Are SAFE\u00ae 2D tubes suitable for storage at \u2212196 \u00b0C?&#8221; tab_id=&#8221;1777974813047-88f86172-5f03&#8243;][vc_column_text css=&#8221;&#8221;]SAFE\u00ae 2D tubes are designed for cryogenic applications down to \u2212196 \u00b0C.<\/p>\n<p>In validation tests, they were exposed to 168 hours of LN\u2082 vapor. No nitrogen ingress was detected. Measured mass loss was below 0.1%.<\/p>\n<p>Material, threads, and seals remained functionally stable.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;What material are SAFE\u00ae 2D tubes made of?&#8221; tab_id=&#8221;1777974813064-09d0cc34-1e4c&#8221;][vc_column_text css=&#8221;&#8221;]SAFE\u00ae 2D tubes are made of SAFE\u00ae L3 Medical Polypropylene.<\/p>\n<p>This polymer is additive-free and contains no slip agents, mold release agents, or co-monomers. It is USP Class VI compliant and has a homogeneous polymer structure.<\/p>\n<p>Analytical tests using GC-MS and LC-MS showed no relevant leachables or extractables. ICP-MS analyses confirmed the absence of detectable heavy metals above the detection limits.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;How is secure sealing ensured during cryogenic storage?&#8221; tab_id=&#8221;1777974813088-3b3c0608-78c3&#8243;][vc_column_text css=&#8221;&#8221;]SAFE closure systems use an axially acting TPE seal concept. O-rings are intentionally omitted, as they may lose elasticity or develop compression set under cryogenic conditions.<\/p>\n<p>Sealing performance was validated at a defined torque of 7 Ncm (for SBS 96) and 15 Ncm (for SBS 48 and SBS 24).<\/p>\n<p>After 15 automated open\/close cycles, mechanical stress, and cryogenic exposure, no leakage, thread abrasion, or seal surface damage was observed.[\/vc_column_text][\/vc_tta_section][\/vc_tta_accordion][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=&#8221;Traceability &#038; Data Integration&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23363636&#8243; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_empty_space][vc_tta_accordion section_title_tag=&#8221;h3&#8243; style=&#8221;flat&#8221; color=&#8221;blue&#8221; spacing=&#8221;5&#8243; c_position=&#8221;left&#8221; active_section=&#8221;&#8221; no_fill=&#8221;true&#8221; collapsible_all=&#8221;true&#8221; faq_schema=&#8221;yes&#8221; el_class=&#8221;gf-faq-schema&#8221;][vc_tta_section title=&#8221;How do 2D DataMatrix tubes support traceability?&#8221; tab_id=&#8221;1777974906717-e31918ff-d5c9&#8243;][vc_column_text css=&#8221;&#8221;]The deeply engraved 2D code enables unambiguous machine-readable identification of each individual sample.<\/p>\n<p>Combined with rack readers and LIMS systems, this creates a consistent digital sample history from receipt to archiving or analysis.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Can SAFE\u00ae 2D tubes be integrated into a LIMS?&#8221; tab_id=&#8221;1777974906772-82358236-5bab&#8221;][vc_column_text css=&#8221;&#8221;]Yes. The codes are standardized for reading and can be directly transferred to LIMS systems. This reduces manual entry errors and supports the digital documentation chain.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Is additional side labeling possible?&#8221; tab_id=&#8221;1777974906821-a11a6116-692e&#8221;][vc_column_text css=&#8221;&#8221;]Optionally, a 1D or HR side label can be added alongside the 2D code.<\/p>\n<p>Additionally, a <a href=\"https:\/\/lvl-technologies.com\/en\/tube_laser_marker\/tlm864\/\" target=\"_blank\" rel=\"noopener\">SAFE\u00ae Tube Laser Marker (TLM)<\/a> can apply a material-integrated laser marking. This remains permanently readable at \u2212196 \u00b0C and, unlike labels, is not affected by condensation or cold stress.[\/vc_column_text][\/vc_tta_section][\/vc_tta_accordion][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=&#8221;Applications &#038; Benefits&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23363636&#8243; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_empty_space][vc_tta_accordion section_title_tag=&#8221;h3&#8243; style=&#8221;flat&#8221; color=&#8221;blue&#8221; spacing=&#8221;5&#8243; c_position=&#8221;left&#8221; active_section=&#8221;&#8221; no_fill=&#8221;true&#8221; collapsible_all=&#8221;true&#8221; faq_schema=&#8221;yes&#8221; el_class=&#8221;gf-faq-schema&#8221;][vc_tta_section title=&#8221;What applications are SAFE\u00ae 2D sample tubes suitable for?&#8221; tab_id=&#8221;1777974976453-879ff955-bc7c&#8221;][vc_column_text css=&#8221;&#8221;]SAFE\u00ae 2D sample tubes are used in biobanking, pharmaceutical research, molecular diagnostics, high-throughput screening, and forensic applications.<\/p>\n<p>They are suitable for environments requiring long-term archiving, automation, and digital traceability.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;What advantages do 2D tubes offer in laboratory automation?&#8221; tab_id=&#8221;1777974976496-e5be0cda-16aa&#8221;][vc_column_text css=&#8221;&#8221;]SAFE\u00ae 2D tubes enable automated scanning, handling, and archiving.<\/p>\n<p>In a validated pick-and-place test with 3,465 cycles, an error rate of 0.086 % was measured. No process interruptions occurred.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;How do SAFE\u00ae 2D tubes reduce sources of error?&#8221; tab_id=&#8221;1777974976530-ee457d67-f99a&#8221;][vc_column_text css=&#8221;&#8221;]Through unambiguous machine-readable identification, precise dimensional accuracy, validated sealing systems, and systemic tube\u2013cap\u2013rack validation, confusion and interface risks are minimized.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;What role do 2D tubes play in regulatory compliance?&#8221; tab_id=&#8221;1777975063992-39c9381d-3194&#8243;][vc_column_text css=&#8221;&#8221;]In GMP-adjacent environments, traceable documentation is essential.<\/p>\n<p>SAFE\u00ae 2D tubes support this through unique ID generation, documented validation, consistent LIMS integration, and material-integrated marking.[\/vc_column_text][\/vc_tta_section][\/vc_tta_accordion][vc_empty_space][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_empty_space][vc_custom_heading text=&#8221;SAFE\u00ae 2D Tubes FAQ \u2013 Formats, Applications &#038; Benefits&#8221; font_container=&#8221;tag:h1|text_align:left|color:%23009fe3&#8243; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_empty_space][vc_column_text css=&#8221;&#8221;]SAFE\u00ae 2D tubes from LVL technologies are specialized sample containers designed for secure, automatable, and traceable storage [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"class_list":["post-62184","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.9 (Yoast SEO v26.9) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>SAFE\u00ae 2D Tubes FAQ \u2013 Formats, Benefits &amp; Applications | LVL technologies<\/title>\n<meta name=\"description\" content=\"FAQ on SAFE\u00ae 2D tubes: Formats, cryogenic storage, traceability &amp; LIMS integration. 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