{"id":47929,"date":"2024-06-19T13:27:49","date_gmt":"2024-06-19T11:27:49","guid":{"rendered":"https:\/\/lvl-technologies.com\/casestudy\/eu-openscreen\/"},"modified":"2026-01-29T12:02:22","modified_gmt":"2026-01-29T11:02:22","slug":"44616","status":"publish","type":"casestudy","link":"https:\/\/lvl-technologies.com\/en\/casestudy\/44616\/","title":{"rendered":"EU Openscreen"},"content":{"rendered":"

[vc_row][vc_column][vc_custom_heading text=”Automated Sample Storage in Europe\u2019s Largest Screening Network for Chemical Biology” font_container=”tag:h2|text_align:center” css=””][vc_empty_space height=”100px”][vc_column_text css=””]EU-OPENSCREEN operates a publicly accessible database containing a unique collection of chemical substances. With more than 20 connected high-throughput screening and chemistry facilities at partner sites across ten European countries, EU-OPENSCREEN provides researchers with access to leading technologies to explore and develop their own bioactive compounds.<\/p>\n

Process of Automated Sample Storage<\/h3>\n

For the highly complex process of automated storage of substances in dimethyl sulfoxide (DMSO) at \u201320\u202f\u00b0C, LVL SAFE\u00ae 2D Tubes and Racks<\/strong> from LVL technologies are used\u2014together with the LVL SAFE\u00ae 8-channel and 96-channel Capper\/Decapper<\/strong>.<\/p>\n

Thanks to the high quality and tight sealing of the tubes, the reliable readability of the codes, and excellent compatibility with automated systems, a smooth workflow is ensured. More than 100,000 samples have already been stored in LVL SAFE\u00ae 2D Tubes<\/strong>.<\/p>\n

Synergy of Chemical Expertise and Biomedicine<\/h2>\n

Biologically active compounds are used in numerous fields, including pharmaceuticals, crop protection, cosmetics, the food industry, and environmental protection. A key technology for discovering new bioactive substances is high-throughput screening of large compound libraries.<\/p>\n

EU-OPENSCREEN is a European Research Infrastructure Consortium (ERIC<\/strong>) focused on chemical biology and the early identification of bioactive compounds. Its goal is to provide scientists in Europe with access to individually selected compounds for scientific studies and experiments.<\/p>\n

The scope ranges from transferring thousands of substances at fixed concentrations to the detailed provision of individual compounds at variable dosages for subsequent development steps. Bioassays to assess biological activity are also conducted.<\/p>\n

Samples and Processes<\/h2>\n
    \n
  1. Lieferung neuer Substanzen in LVL SAFE\u00ae 2D Tubes<\/strong><\/li>\n
  2. Probenprozessierung im Pipettierroboter<\/li>\n
  3. Automatisiertes Capping\/Decapping mit dem LVL SAFE\u00ae 96-Kanal Capper\/Decapper<\/li>\n
  4. Kontrolliertes Einfrieren und Einlagerung<\/strong> im vollautomatisierten Lagersystem bei \u201320\u202f\u00b0C<\/li>\n
  5. Anfragen europ\u00e4ischer Partner zur Verwendung zu Forschungszwecken<\/li>\n
  6. Automatisierte Probenselektion und \u00dcberf\u00fchrung in MTPs f\u00fcr den Versand<\/li>\n
  7. Nutzung in wissenschaftlichen Studien und Experimenten<\/li>\n<\/ol>\n

    Detailed Process Steps<\/h2>\n